Podcast: Finding a promising target to reduce TB’s tissue-damaging effects

Neetika and sheetal
We are hoping that our research may help in finding a promising target to reduce inflammation in TB patients” say Sheetal Gandotra (left) and Neetika Jaisinghani.

Institute of Genomic and Integrative Biology (CSIR-IGIB), Delhi, researchers have for the first time discovered that necrosis in granulomas result in the development of lipid-rich foamy macrophages, thus overthrowing the general belief that TB bacteria make the host cells accumulate lipids. They also report for the first time that foamy macrophages show more inflammatory response than normal macrophages. So targeting the tissue-damaging effects of inflammation may be helpful in TB patients.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.