IIT Guwahati researchers have developed bioactive wound dressings and bio-artificial skin by using silkworm silk fibroin as matrix and coating it with recombinant spider silk proteins. The recombinant spider silk reduced bacterial population by nearly four-fold and showed good anti-biofilm properties and recruited cells to the site of wound. The skin graft was bilayered (demis and epidermis) and vascularised.