IISER Pune researchers have increased the uptake of poorly water-soluble anticancer drug by loading it in nanovesicles that self-assemble. The nanovesicles can be loaded with both hydrophilic and hydrophobic drugs. The encapsulated drug produced 94% silencing of the target AURKA leading to 25% inhibition of RalA. As a result, there was 38% inhibition of anchorage independent growth of cancer cells — metastasis.
Science Chronicle 