Podcast: Ten-year journey to develop a diagnostic test for TB meningitis


Sagarika Haldar is currently at the Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh.

A team lead by Jaya Sivaswami Tyagi from AIIMS in collaboration with THSTI has developed a diagnostic test for TB meningitis with nearly 100% sensitivity and about 91% specificity. The rapid, point-of-care diagnostic test for TB meningitis, which uses the DNA aptamer, has already been adapted to a sensor format and is being evaluated on clinical samples. It has taken the team 10 years to reach this stage.