Podcast: Increasing the cellular uptake of fluorescent probe using iodine

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Prof. Govindasamy Mugesh explains how the the cellular uptake of fluorescent probe naphthalimide was drastically improved (from 5-8% to up to 98%) by substituting two of its hydrogen atoms with iodine. The iodine atom forms a halogen bond with the MCT8 receptor that ferries the molecule across the membrane. The receptor is known to transport thyroxine, which is a thyroid hormone containing iodine, into the cells.

Published by Prasad Ravindranath

Science Editor with @The_Hindu, Chennai, India. Do get in touch with me at PRASAD.THEHINDU@GMAIL.COM if you have some interesting results that can be published in The Hindu and also in my blog. You can also reach me on Twitter @RPrasad12 and Facebook /prasad.ravindranath. I write on science, health, medicine, environment, and technology.