Podcast: How Klebsiella bacteria develop colistin resistance

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 Ghafur Abdul Ghafur explains how the team deciphered the mechanism by which Klebsiella bacteria develop resistance to colistin, a last-line antibiotic. Mutations and insertional inactivation of the mgrB gene, which is present in the chromosome, are responsible for colistin resistance in Klebsiella. The inserational sequence that moves out from the chromosome to plasmid before spreading to other bacteria helps colistin resistance to spread.

Published by Prasad Ravindranath

Science Editor with @The_Hindu, Chennai, India. Do get in touch with me at PRASAD.THEHINDU@GMAIL.COM if you have some interesting results that can be published in The Hindu and also in my blog. You can also reach me on Twitter @RPrasad12 and Facebook /prasad.ravindranath. I write on science, health, medicine, environment, and technology.