IISER Pune identifies druggable targets for multidrug-resistant Staphylococcus aureus

IISER Pune researchers have identified novel drug targets to kill multidrug-resistant Staphylococcus aureus. They increased the small molecule's ability to cross the cell barrier and bind to multiple proteins. A few proteins are crucial for bacteria's survival. Novel protein targets that can be used by candidate drug molecules to kill antibiotic-resistant strains of Staphylococcus aureus, … Continue reading IISER Pune identifies druggable targets for multidrug-resistant Staphylococcus aureus

IISc: Chemically etched aluminium kills, keep surfaces bacteria-free

Researchers at IISc have produced etched aluminium that is capable of killing Gram-negative bacteria such as E. coli and keep surfaces free of both E. coli and S. aureus. Surfaces that have both micro and nanoscale features are most effective in killing bacteria, drug-resistant bacteria included. These can find ready application in hospitals to prevent hospital-acquired … Continue reading IISc: Chemically etched aluminium kills, keep surfaces bacteria-free

IISc team mimics nature to keep orthopaedic implants bacteria-free

Mimicking tiny features seen on insect wings and shark skin that effectively keep their surfaces free of bacteria, a team from Bengaluru’s Indian Institute of Science (IISc) has found a way to prevent bacterial infection on orthopaedic implants without using any chemicals. The team led by Prof. Kaushik Chatterjee from the Department of Materials Engineering … Continue reading IISc team mimics nature to keep orthopaedic implants bacteria-free

IISc produces a novel salt to better combat bacterial infections

Using crystal engineering, a team of researchers from the Indian Institute of Science (IISc) Bangalore has successfully produced a highly efficacious binary salt of two commonly used drugs — norfloxacin (antibacterial) and sulfathiazole (antimicrobial). The salt is more effective than a physical mixture of the two drugs. The results were published in the journal Molecular Pharmaceutics. … Continue reading IISc produces a novel salt to better combat bacterial infections