A Science and Technology Blog
A molecule identified by IIT Roorkee researchers exhibits broadspectrum bactericidal activity against multidrug-resistant bacteria. The molecule was found to be effective against persister bacteria as well. Screening a small-molecule library…
IISER Pune researchers have identified novel drug targets to kill multidrug-resistant Staphylococcus aureus. They increased the small molecule’s ability to cross the cell barrier and bind to multiple proteins. A…
IACS researchers have fabricated a cytidine-based hydrogel that self-assembles in the presence of silver acetate and boronic acid and exhibits antibacterial activity against Gram-negative bacteria. The hydrogel can be used…
Three cheap, filter-based kits developed by a multi-institutional team and an industry partner improves the sensitivity of LED fluorescence microscopy by 5%, enable transport of sputum samples at ambient conditions…
The 443 cholera-causing Vibrio cholerae isolates isolated from patients from Kolkata and Delhi show very high drug resistance to 22 antibiotics belonging to nine classes. About 99% of the isolates…
Though the total number of people with XDR-TB and treatment intolerant or non-responsive MDR-TB who will require the new anti-TB drug Pretomanid may not be high, these are people who…
When used in combination with bedaquiline and linezolid, the newly approved pretomanid drug for MDR-TB and XDR-TB had an overall treatment success rate of about 90%. Besides better effectiveness, the…
Using a novel drug-delivery approach, IIT Hyderabad researchers have made oral administration of the drug Amphotericin B for treating Kala-azar and fungal infection possible. The drug encapsulated in polymer nanofibres…
