IGIB researchers have for the first time discovered that necrosis in granulomas result in the development of lipid-rich foamy macrophages, thus overthrowing the general belief that TB bacteria make the host cells accumulate lipids. They also report for the first time that foamy macrophages show more inflammatory response than normal macrophages. So targeting the tissue-damaging effects … Continue reading IGIB researchers find ways to reduce TB’s tissue-damaging effects
TB drugs
IGIB shows how fat cells protect TB bacteria from oxidative stress
IGIB researchers found that genes responsible for iron intake were less expressed in TB bacteria found in fat cells. The decreased expression provides protection to TB bacteria from iron-mediated oxidative stress. Different regions of a tissue have different levels of fat and iron, and TB bacteria have the ability to adapt to each condition, thus making … Continue reading IGIB shows how fat cells protect TB bacteria from oxidative stress
ICMR wins the 2017 Kochon Prize for TB research
The Indian Council of Medical Research (ICMR) has won the Stop TB Kochon Prize for excellence in TB research and development. The $65,000 Prize is awarded annually by Stop TB Partnership to individuals and/or organizations that have made a significant contribution to combating TB. The ICMR emerged the winner from amongst 18 nominations. The 2017 Kochon Prize was awarded … Continue reading ICMR wins the 2017 Kochon Prize for TB research
Nandita: Deaf but not out
When she woke up after a short afternoon nap on November 22, 2013, two days after her 24th birthday, Nandita Venkatesan could see her mother and brother talking to her but could understand nothing; she could hear sounds but could not comprehend them. The noisy world around her almost fell silent. Her hearing loss was … Continue reading Nandita: Deaf but not out
Pharmacies in India may not be causing TB drug-resistance
If an earlier study revealed the tendency of private practitioners to liberally use antibiotics to treat tuberculosis leading to a delay in TB diagnosis and treatment and increase the chances of TB spreading within a community, pharmacies in Delhi, Mumbai and Patna are no better. A study published on August 25, 2016 in the journal … Continue reading Pharmacies in India may not be causing TB drug-resistance
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