IGIB finds a protein with better gene editing precision

IGIB researchers have used a different Cas9 protein derived from another bacteria to make gene editing more efficient and precise. The new Cas9 protein shows very less tendency to bind to off-target (unintended) sites on DNA. The new Cas9 protein was able to correct sickle cell anaemia mutation in patient-derived stem cells. Researchers at the Delhi-based … Continue reading IGIB finds a protein with better gene editing precision

Scientists edit a disease-causing mutation from genes in human embryos

As scientists repair a genetic mutation in a human embryo, the ethical debate has been revived. Scientists have for the first time managed to edit genes in a human embryo to repair a genetic mutation, fuelling hopes that such procedures may one day be available outside laboratory conditions. In results announced in Nature a few days … Continue reading Scientists edit a disease-causing mutation from genes in human embryos