Rheumatoid arthritis: CDRI’s peptide effective in preventing cartilage destruction

CDRI researchers have used a specific fragment of a protein secreted by the parasitic worm liver fluke to protect the cartilage of joints from being destroyed, thus preventing rheumatoid arthritis from progressing. The peptide does not cause a wholesale suppression of the immune system. A specific fragment of a protein secreted by the parasitic worm … Continue reading Rheumatoid arthritis: CDRI’s peptide effective in preventing cartilage destruction

IIT researchers 3D bioprint load-bearing bones

Researchers from IIT Delhi and IIT Kanpur have used a different approach to mimic the development biology pathway by which adult load-bearing bones are formed. The researchers made the stem cells to first differentiate into cartilage, and the cartilage was then converted into bones. The bones tissue engineered showed more similarity to limb skeleton development … Continue reading IIT researchers 3D bioprint load-bearing bones

Podcast: Fabricating a scaffold for cartilage repair

Yogendra Pratap Singh from IIT Guwahati explains how the biphasic scaffold fabricated using silk is superior to the existing ones. Since the entire scaffold is made of silk, the junction between the half that is spongy and mimics the cartilage while the other half is less porous and mimics the bone is seamless. In rabbits, … Continue reading Podcast: Fabricating a scaffold for cartilage repair

IIT Guwahati fabricates superior scaffold for cartilage repair

Using silk, researchers from IIT Guwahati have fabricated a biphasic scaffold where one half is spongy and mimics the cartilage while the other half is less porous and mimics the bone. The junction between the two phases is seamless. In rabbits, the fibre-reinforced scaffold allowed more bone formation, while the cartilage was regenerated and completely … Continue reading IIT Guwahati fabricates superior scaffold for cartilage repair

IIT Kanpur researchers find why babies need to move in the womb

IIT Kanpur researchers have found how permanent cartilage is formed in an embryo due to mechanical movement. The permanent cartilage gets lost and transient cartilage forms in its place in the absence of movement. In the developing embryos, the joints do not form at all if movement is restricted. Studies are on to find out if it … Continue reading IIT Kanpur researchers find why babies need to move in the womb

Indian researchers develop 3D bioprinted cartilage

Millions of people around the world suffer from degenerative joint diseases such as arthritis. Despite attempting for the last 30 years, scientists across the world have not been able to produce in the lab cartilage-like tissues that are functionally and structurally similar to cartilages seen in human knees and have load-bearing capacity. For the first … Continue reading Indian researchers develop 3D bioprinted cartilage