The world's first human challenge trial for a vaccine against SARS-CoV-2 is set to begin in London in January. Human challenge trials for the SARS-CoV-2 virus have many challenges, including producing a strain that is less virulent, but Dr. Gagandeep Kang says such trials can provide information and help design better vaccines than we can do now with conventional trials.
Controlled human infection model (CHIM)
WHO backs COVID-19 vaccine trials that deliberately infect participants
In new guidelines issued on May 6, WHO has backed human challenge studies for COVID-19 vaccines on the ground that it could both accelerate vaccine development and make the final vaccine far more effective. In new guidelines issued on May 6, the World Health Organization has said that well-designed human challenge studies could not only … Continue reading WHO backs COVID-19 vaccine trials that deliberately infect participants
CHIM: Infecting healthy people with coronavirus can speed up vaccine trials
While conventional human clinical trials of novel coronavirus vaccine will take 12-18 months to complete, the human challenge studies can speed up the process and help complete the trial by the end of the year. Even if everything goes to plan, it will take at least 12-18 months for a novel coronavirus (SARS-CoV-2) vaccine to … Continue reading CHIM: Infecting healthy people with coronavirus can speed up vaccine trials