Using a novel drug-delivery approach, IIT Hyderabad researchers have made oral administration of the drug Amphotericin B for treating Kala-azar and fungal infection possible. The drug encapsulated in polymer nanofibres and made into tablets was released in a controlled and sustained manner for 10 days. By encapsulating an antifungal drug in polymer nanofibres, researchers at … Continue reading IIT Hyderabad: A step closer to oral administration of Kala-azar drug
Kala-azar
Novel inhibitor to combat kala-azar identified
A FDA-approved molecule identified through structure-based drug designing methodology has been found to be effective against kala-azar. In vitro studies show the molecule to be less toxic than the drug currently being used to treat kala-azar. Combining structure-based drug designing methodology with in vitro studies, scientists have been able to identify a FDA-approved molecule that shows enhanced … Continue reading Novel inhibitor to combat kala-azar identified
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