A Science and Technology Blog
IISER Pune researchers have identified novel drug targets to kill multidrug-resistant Staphylococcus aureus. They increased the small molecule’s ability to cross the cell barrier and bind to multiple proteins. A…
When used in combination with bedaquiline and linezolid, the newly approved pretomanid drug for MDR-TB and XDR-TB had an overall treatment success rate of about 90%. Besides better effectiveness, the…
A novel compound isolated from a soil bacterium by IMTECH researchers shows promise in killing Gram-negative bacteria (Klebsiella pneumoniae and E. coli) that are resistant to colistin. Compared with colistin,…
JNCASR researchers along with French counterparts have been able to fully restore neuron to neuron connections and long-term memory in mice with Alzheimer’s disease using a small molecule that activates…
Amit Singh from IISc explains how a protein (WhiB4) that condenses the DNA of TB-causing bacteria in response to oxidative stress was identified. The team found that artificially elevating the…
IISc researchers have for the first time identified a protein (WhiB4) that condenses the DNA of TB-causing bacteria in response to oxidative stress. They found that artificially elevating the levels of WhiB4…
Scientists from AIIMS, THSTI and IIT Indore have successfully been able to inhibit the entry of TB bacteria into host cells by using aptamer-based inhibitor that binds to the HupB protein…
A team of researchers from three institutions in India has used aptamer-based inhibitor that binds to the HupB protein found on TB bacteria cell surface to significantly inhibit the entry…
