A Science and Technology Blog
Of the two small molecules tested, IIT Roorkee researchers have found one of them has good antiviral activity against chikungunya virus. The small molecule was able to achieve almost 99% reduction…
A team led by researchers from JNU and ICGEB, New Delhi has identified a molecule that prevents malaria parasites from invading red blood cells (RBCs) and causing the disease. It prevents the…
A FDA-approved molecule identified through structure-based drug designing methodology has been found to be effective against kala-azar. In vitro studies show the molecule to be less toxic than the drug currently being…
The Piperazine drug used for treating worm infections and HIV has been able to inhibit the replication of chikungunya virus by nearly 98%. A drug to treat chikungunya virus infection is in…
Four-stranded DNA structures known as G-quadruplexes, which are present in human genome, can control the activities of cancer-causing genes and hence have emerged as anticancer drug targets. Scientists at the…
A novel small molecule designed and synthesised by Indian researchers has shown promise in targeted killing of cancer cells. The molecule (Disarib) binds to a protein BCL2 and inhibits the…
In a completely different approach to drug discovery, a team led by Dr. Samir K. Brahmachari at Delhi’s CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB) has used a combination of…
Scientists at the Indian Institute of Science (IISc) Bengaluru have developed two new, potent molecules that can severely impact the survival of mycobacteria, including Mycobacterium tuberculosis that causes TB. The…
