Podcast: Role of OVGP1 protein in embryo implantation

Mumbai-based researchers have discovered how the embryo signals the endometrium to express the OVGP1 protein for a brief period at the time of implantation. They found that the OVGP1 protein is required for balancing the expression of a few genes required for embryo implantation. This work in long term might have implications in management of … Continue reading Podcast: Role of OVGP1 protein in embryo implantation

Mumbai team discovers the novel role of OVGP1 protein in embryo implantation

Mumbai-based researchers have discovered how the embryo signals the endometrium to express the OVGP1 protein for a brief period at the time of implantation. They found that the OVGP1 protein is required for balancing the expression of a few genes required for embryo implantation. This work in long term might have implications in management of … Continue reading Mumbai team discovers the novel role of OVGP1 protein in embryo implantation

Treating latent TB of the uterus improves pregnancy outcomes in infertile women

Indian researchers have for the first time found an association between latent TB of the endometrium and fewer eggs in the ovary (low ovarian reserve) in infertile women. Though how latent TB actually causes this reduction is not known, treating the infection led to significant improvement in pregnancy outcomes in infertile women. For the first … Continue reading Treating latent TB of the uterus improves pregnancy outcomes in infertile women

Indian researcher develops smartphone-based device for male infertility screening

An Indian and a team of researchers from Harvard Medical School, Boston have developed a smartphone-based semen analyser that will go a long way in identifying the cause of infertility in men — low sperm concentration and motility —with nearly 98% accuracy. The portable, easy to use, automated device can be used by untrained individuals, … Continue reading Indian researcher develops smartphone-based device for male infertility screening

Mumbai researchers identify a protein critical for sperm motility

A Mumbai-based team of researchers has identified one more protein — heat shock protein 90 (HSP90) — found in human sperm that determines the ability of sperm to vigorously whip their tail and move or swim (motility) faster towards an egg to fertilise it. The reduced ability of sperm to move towards the egg is … Continue reading Mumbai researchers identify a protein critical for sperm motility

IISc: endosulfan induces infertility in male mice

If an association between the widely used pesticide, endosulfan and male infertility has been found in the case of humans living in areas where it has been extensively used, laboratory studies on mice have now confirmed that the pesticide indeed causes male infertility. A significant reduction in sperm count and sperm motility in mice was … Continue reading IISc: endosulfan induces infertility in male mice