IIT Kanpur team identifies a novel target to treat prostate cancer

Researchers at IIT Kanpur have discovered that a particular gene (DLX1), which plays an important role in the development of jaws, skeleton, and interneurons in the brain, has an important role to play in the growth and development of prostate cancer. Researchers at the Indian Institute of Technology (IIT) Kanpur have discovered that a particular … Continue reading IIT Kanpur team identifies a novel target to treat prostate cancer

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People above 45 years with comorbidities will need doctor certificate, says task force member

Those older than 45 years and with comorbidities will need a certificate from a registered medical doctor. But those older than 60 years will not need any certificate. only Serum Institute’s Covishield vaccine will be available at private hospitals. Self-registration needed for those above 45 years with comorbidities.

CRISPR-Cas9 gene-editing technology: In a first, an all-women team wins the Nobel Prize

That scientists who pioneered the revolutionary CRISPR-Cas9 gene-editing technology, the biggest game-changer in biology in recent years, will win the Nobel Prize was never in doubt; it was only a question of when and who would get recognised for the work done to develop the tool.

A safer alternative approach to treat aggressive prostate cancer found

A multi-institutional team led by IIT Kanpur has found the mechanism responsible for the aggressive return of prostate cancer in treated patients. They also found that treating prostate cancer cells showing elevated SPINK1 protein with a drug against Casein Kinase 1 resulted in reduced cancer cell growth as well as aggressiveness. A study shows why … Continue reading A safer alternative approach to treat aggressive prostate cancer found

Potential biomarkers for glioma brain tumour found in blood

Researchers have found potential gene biomarkers that can be used for prognosis and early diagnosis of primary brain tumour glioblastoma. The biomarkers can also indicate the chances of survival of patients with glioma. Researchers have found potential gene biomarkers that can be used for prognosis and early diagnosis of the most aggressive form of primary … Continue reading Potential biomarkers for glioma brain tumour found in blood

IIT Hyderabad team uses plant extract, heat to kill cancer cells

IIT Hyderabad used chlorophyll-rich extract of a medicinal plant encapsulated in nanoparticles along with a dye to kill cancer cells when exposed to near-infrared light. The cancer cells were killed through reactive oxygen species-mediated autophagy. The extract was selective in killing only cancer cells. Lipid-based nanoparticles encapsulating chlorophyll-rich extract of a medicinal plant Anthocephalus cadamba and … Continue reading IIT Hyderabad team uses plant extract, heat to kill cancer cells

IISc: Natural shield protects certain DNA regions from radiation damage

IISc researchers found that certain regions of the genome rich in four-stranded DNA  — G-quadruplexes (G4-DNA) — are more resistant to radiation damage. As a result, there are fewer DNA breaks seen in G-quadruplexes when exposed to radiation. It is well known that ionizing radiation can break the double-stranded DNA in one or both the strands. … Continue reading IISc: Natural shield protects certain DNA regions from radiation damage

Machine learning-based model can determine if skin cancer can spread

Using machine learning of 17 genomic signatures, researchers from IIIT Delhi and CSIR-IMTECH have developed a webserver called CancerSPP that will help clinicians in classifying cutaneous melanoma as either primary or metastatic. The accuracy is over 89%, and both sensitivity and specificity are high. Using the expression of 17 key genes (messenger RNAs) it is … Continue reading Machine learning-based model can determine if skin cancer can spread

Aflatoxin in milk raises safety concerns

Of the over 6,400 samples collected from 1,100 towns/cities in India, 93% were found to be safe. But 5.7% had aflatoxin M1 residues beyond the permissible limit. The highest levels of aflatoxin M1 residue in milk were seen in three States — Tamil Nadu, Delhi and Kerala. International Agency for Research on Cancer (IARC) has … Continue reading Aflatoxin in milk raises safety concerns

Delhi team fabricates a sensor to detect drug-resistant leukaemia

A highly sensitive carbon nanotube-based sensor capable of detecting multidrug-resistant myeloid leukemia cells even when present at very low concentration of 10 cells per ml has been fabricated by Delhi-based researchers. Using chemical vapour deposition technique, the team led by Prof. S.S. Islam from the Centre for Nanoscience and Nanotechnology at the Jamia Millia Islamia … Continue reading Delhi team fabricates a sensor to detect drug-resistant leukaemia