Kolkata researchers use novel compound to kill cancer cells

Twenty-five quinoline derivatives synthesised by IICB researchers and tested in the lab by IACS team show potent anticancer activity. The mode of action is the same for current drugs and the compounds tested. The difference is that topoisomerase 1-DNA complexes remain trapped for a longer time when the compounds are used and so have greater … Continue reading Kolkata researchers use novel compound to kill cancer cells

IACS researchers use a novel compound to kill cancer cells

IACS researchers have synthesised a novel porphyrin compound that shows potent anticancer activity. The porphyrin compound selectively targets and binds to cellular topoisomerase 1 enzyme, which is essential for maintenance of DNA architecture in the cells, found in cancer cells and causes cell death. Researchers at Kolkata’s Indian Association for the Cultivation of Science (IACS) … Continue reading IACS researchers use a novel compound to kill cancer cells

Diagnosing early-stage cervical cancer using artificial intelligence

Using an artificial intelligence-based algorithm that uses scattered light data from tissues, researchers from IISER Kolkata and IIT Kanpur have been able to differentiate normal and precancerous tissue, and even identify the different stages of progression of the disease within a few minutes and with great accuracy. In vivo studies are now being carried out. … Continue reading Diagnosing early-stage cervical cancer using artificial intelligence

IIT teams developing a self test for cervical cancer

A team of researchers led by Dr. Aravind Kumar Rengan from IIT Hyderabad is attempting to quantify the visual inspection with acetic acid (VIA) technique for cervical cancer so it becomes technician-independent. The ultimate goal is to develop a self test for cervical cancer. A pap smear, a gold standard test, for cervical cancer screening may … Continue reading IIT teams developing a self test for cervical cancer

IIT teams use elevated enzyme in cancer cells for diagnosis

Cancer cells can be distinguished from normal cells by the colour of the emission. The presence of yellow emission indicates normal cells while blue indicates cancer cells. Researchers at the Indian Institute of Technology (IIT) Ropar, Punjab and IIT Mandi, Himachal Pradesh have utilised the overexpression of biotin receptors on cancer cells and enhanced production … Continue reading IIT teams use elevated enzyme in cancer cells for diagnosis

Growing interest in HPV vaccination in India

Delhi and Punjab have introduced HPV vaccination and are expanding it, while a few States have shown interest. And the National Technical Advisory Group on Immunisation is considering the introduction of HPV vaccination as part of the Universal Immunisation Programme. After the suspension of the human papillomavirus (HPV) vaccine trial in 2010 carried out on … Continue reading Growing interest in HPV vaccination in India

Mumbai team a step closer to treating oral cancer without surgery

If photothermal ablation is successful in humans, oral cancer can be treated in 30-40 minutes as an outpatient service. Researchers in Mumbai have moved a step closer to treating surface tumours such as oral, breast and cervical cancer and other tumours such melanoma and colon cancer through photothermal ablation using gold-polymer nanoparticles and near infrared … Continue reading Mumbai team a step closer to treating oral cancer without surgery

IISER Pune researchers produce a novel drug-delivery system to kill cancer cells

Researchers at the Indian Institute of Science Education and Research (IISER) Pune have developed a novel cancer drug-delivery system using graphene oxide nanoparticles. In a serendipitous discovery, a team led by Dr. Sudipta Basu and Dr. Nirmalya Ballav from the Department of Chemistry found that when a FDA-approved anticancer drug cisplatin was added, the graphene … Continue reading IISER Pune researchers produce a novel drug-delivery system to kill cancer cells

Novel molecule synthesised by Indian researchers shows promise in treating cancer

A novel small molecule designed and synthesised by Indian researchers has shown promise in targeted killing of cancer cells. The molecule (Disarib) binds to a protein BCL2 and inhibits the protein from suppressing cell death in cancer cells. While BCL2 protein is produced in excess in cancer cells, its expression is almost undetectable in normal … Continue reading Novel molecule synthesised by Indian researchers shows promise in treating cancer

India turns spotlight on adolescent health

“India has demonstrated very strong leadership in positioning adolescent health as part of continuum of care. India has taken the lead to present to the rest of the States why it is important to have a discussion on adolescent health,” said Dr. Flavia Bustreo, Assistant Director-General of Family, Women’s and Children’s Health, WHO, Geneva. She … Continue reading India turns spotlight on adolescent health