Kolkata researchers use novel compound to kill cancer cells

Twenty-five quinoline derivatives synthesised by IICB researchers and tested in the lab by IACS team show potent anticancer activity. The mode of action is the same for current drugs and the compounds tested. The difference is that topoisomerase 1-DNA complexes remain trapped for a longer time when the compounds are used and so have greater … Continue reading Kolkata researchers use novel compound to kill cancer cells

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IACS researchers use a novel compound to kill cancer cells

IACS researchers have synthesised a novel porphyrin compound that shows potent anticancer activity. The porphyrin compound selectively targets and binds to cellular topoisomerase 1 enzyme, which is essential for maintenance of DNA architecture in the cells, found in cancer cells and causes cell death. Researchers at Kolkata’s Indian Association for the Cultivation of Science (IACS) … Continue reading IACS researchers use a novel compound to kill cancer cells