IIT Kanpur team identifies a novel target to treat prostate cancer

Researchers at IIT Kanpur have discovered that a particular gene (DLX1), which plays an important role in the development of jaws, skeleton, and interneurons in the brain, has an important role to play in the growth and development of prostate cancer. Researchers at the Indian Institute of Technology (IIT) Kanpur have discovered that a particular … Continue reading IIT Kanpur team identifies a novel target to treat prostate cancer

A safer alternative approach to treat aggressive prostate cancer found

A multi-institutional team led by IIT Kanpur has found the mechanism responsible for the aggressive return of prostate cancer in treated patients. They also found that treating prostate cancer cells showing elevated SPINK1 protein with a drug against Casein Kinase 1 resulted in reduced cancer cell growth as well as aggressiveness. A study shows why … Continue reading A safer alternative approach to treat aggressive prostate cancer found

IIT Kanpur team unravels molecular mechanism of a prostate cancer subtype

IIT Kanpur-led team discovers the molecular mechanism by which a protein (EZH2) is produced in excess leading to a reduction in the levels of two microRNAs. This causes an oncogene (SPINK1) to get overexpressed in the SPINK1-positive prostate cancer subtype.  Synthetic microRNAs and epigenetic drugs that increase the microRNA levels reduce tumour growth and metastasis. … Continue reading IIT Kanpur team unravels molecular mechanism of a prostate cancer subtype

IIT Gandhinagar team takes initial step to treat breast, prostate cancer

IIT Gandhinagar researchers have successfully produced large quantity of a biologically active protein involved in DNA damage response pathway in breast and prostate cancer cells. A handful of small molecules synthesised by them was able to achieve up to 75% inhibition of the protein thus preventing it from repairing DNA damage in cancer cells caused by radiation or … Continue reading IIT Gandhinagar team takes initial step to treat breast, prostate cancer