TIFR researchers discover a novel function of serotonin

In a surprising discovery, TIFR researchers have found a novel function for serotonin — generation of new mitochondria in neurons, increased cellular respiration and ATP production. The team found that serotonin reduces reactive oxygen species, thus providing neuroprotection against cellular stress. In a surprising discovery, researchers at the Tata Institute of Fundamental Research (TIFR) Mumbai … Continue reading TIFR researchers discover a novel function of serotonin

Podcast: Drug target to treat Parkinson’s, Alzheimer’s and cancer discovered

Researchers at the Institute of Life Sciences, Bhubaneswar have identified the novel mechanism by which misfolded proteins form aggregates and get degraded in the cells. They have discovered that downregulation of TRIM16 protein may help in treating cancers, while activation of the TRIM16 protein may have therapeutic benefits in the case of neurodegerative diseases such as … Continue reading Podcast: Drug target to treat Parkinson’s, Alzheimer’s and cancer discovered

Bhubaneswar team discovers a drug target for neurodegenerative diseases, cancer

Institute of Life Sciences researchers have discovered that downregulation of a protein drug target can help in the treatment of cancers, while activation can do the same for neurodegerative diseases such as Alzheimer’s, Parkinson’s and amyotrophic lateral sclerosis. They have identified the novel mechanism by which misfolded proteins form aggregates and get degraded in the cells. … Continue reading Bhubaneswar team discovers a drug target for neurodegenerative diseases, cancer

IISc team designs a nanomaterial to treat Parkinson’s

A metal oxide nanomaterial capable of mimicking all three major cellular antioxidant enzymes that control the level of reactive oxygen species (ROS) inside cells has been designed. These nanozymes possess therapeutic potential to prevent ROS-mediated neurological disorders such as Parkinson's disease. A team of researchers from the Indian Institute of Science (IISc) Bengaluru has fabricated a … Continue reading IISc team designs a nanomaterial to treat Parkinson’s

IIT Madras’ baby steps to develop data glove for the speech-disabled

A data glove, which measures the individual joint angles of all the five fingers to understand the activity daily living, developed by Nayan Bhatt, Research Scholar from the Department of Applied Mechanics, IIT Madras recently won the Budding Innovators Award given by the Delhi-based National Research Development Corporation (NRDC). He has been working on developing … Continue reading IIT Madras’ baby steps to develop data glove for the speech-disabled

IIT Bombay researchers a step closer to treating Parkinson’s disease

Researchers from the Indian Institute of Technology, Bombay (IIT B) have taken the first successful step at regenerating neurons in a Parkinson mouse model by using mesenchymal stem cells (MSCs) encapsulated in an amyloid hydrogel. The hydrogels, which provide scaffolding for stem cells to develop into neurons when implanted in the brain, are developed from … Continue reading IIT Bombay researchers a step closer to treating Parkinson’s disease

Indian researchers show cancer drugs can stop the progression of Alzheimer’s, Parkinson’s

In a breakthrough, researchers from the University of Delhi found that the progression of Alzheimer’s and Parkinson’s diseases can be suppressed or stopped by downregulating the expression level of d-myc in Drosophila (fruit fly).  Since d-myc in an evolutionarily conserved human homolog of c-myc proto-oncogene, the findings in fruit fly may be applicable to humans … Continue reading Indian researchers show cancer drugs can stop the progression of Alzheimer’s, Parkinson’s

One step closer to treating neurodegenerative diseases

Published in The Hindu on August 20, 2009 Treating neurodegenerative diseases has got a shot in the arm. A scientist from the Tel Aviv University (TAU) has been able to observe the stem cells injected in an animal model with Huntington’s disease repairing the damaged tissues. A pre-clinical study using NTFs was undertaken last year … Continue reading One step closer to treating neurodegenerative diseases