Podcast: Increasing the cellular uptake of fluorescent probe using iodine

Prof. Govindasamy Mugesh explains how the the cellular uptake of fluorescent probe naphthalimide was drastically improved (from 5-8% to up to 98%) by substituting two of its hydrogen atoms with iodine. The iodine atom forms a halogen bond with the MCT8 receptor that ferries the molecule across the membrane. The receptor is known to transport thyroxine, which is a … Continue reading Podcast: Increasing the cellular uptake of fluorescent probe using iodine

IISc team uses iodine to increase cellular uptake of fluorescent probe

IISc researchers have drastically improved (up to 98%) the cellular uptake of fluorescent probe naphthalimide by substituting two of its hydrogen atoms with iodine. The iodine atom forms a halogen bond with the MCT8 receptor that ferries the molecule across the cell membrane. The probe molecule with iodine will also help in studying the uptake of thyroid hormone. By … Continue reading IISc team uses iodine to increase cellular uptake of fluorescent probe