Combination therapy using malaria drug quickly clears TB
IISc researchers have discovered the mechanism by which TB bacteria develop tolerance to TB drugs. They found a combination of malaria and TB drug can prevent the bacteria from developing…
Category: Isoniazid
Cheap, filter-based kits developed for TB diagnosis, drug-resistance testing
Three cheap, filter-based kits developed by a multi-institutional team and an industry partner improves the sensitivity of LED fluorescence microscopy by 5%, enable transport of sputum samples at ambient conditions…
Delhi researchers find diabetic drug improves the efficacy of two TB drugs
Delhi researchers have identified a protein that is vital for the formation of biofilm by TB-causing bacteria and other bacterial species. Two FDA-approved drugs (acarbose and cyclosporine-A) bind to the…
Podcast: FDA-approved asthma drug effectively treats TB
Archita Mishra and other researchers from IISc found that a FDA-approved asthma drug can be used for treating TB. Laboratory studies found the drug to be more effective in curtailing…
IISc researchers find asthma drug effective in treating TB
Researchers at IISc used a FDA-approved asthma drug to treat TB. Laboratory studies found the drug to be more effective in curtailing the growth of TB bacteria when used alone…
IGIB shows how fat cells protect TB bacteria from oxidative stress
IGIB researchers found that genes responsible for iron intake were less expressed in TB bacteria found in fat cells. The decreased expression provides protection to TB bacteria from iron-mediated oxidative stress.…
A looming threat of tuberculosis in children
The RNTCP guidelines on contact screening are heeded mostly in the breach. About 5,500 of over 76,000 children tested in nine Indian cities have been diagnosed with tuberculosis, 9% of…
Pilot testing of bedaquiline drug on TB patients to start soon
A pilot programme to test the toxicity, particularly cardio-toxicity, of bedaquiline drug (used for combating multidrug-drug resistant TB) in the Indian population, assess its ability to achieve culture conversion and…
