Pretomanid: XDR-TB may soon become easily treatable
Though the total number of people with XDR-TB and treatment intolerant or non-responsive MDR-TB who will require the new anti-TB drug Pretomanid may not be high, these are people who…
Category: MDR-TB
Explainer: What makes the new drug-resistant TB medicine Pretomanid promising
When used in combination with bedaquiline and linezolid, the newly approved pretomanid drug for MDR-TB and XDR-TB had an overall treatment success rate of about 90%. Besides better effectiveness, the…
Majority of MDR-TB cases in India due to direct transmission: Lancet
While India has set a highly ambitious target of “eliminating TB by 2025”, modelling studies published today say incidence and mortality will reduce by just 57% and 72% respectively by…
Small DNA-based inhibitor blocks entry of TB bacteria into host cells
A team of researchers from three institutions in India has used aptamer-based inhibitor that binds to the HupB protein found on TB bacteria cell surface to significantly inhibit the entry…
MDR-TB treatment gets a boost with the inclusion of bedaquiline in the fully-oral regimen
In a “rapid communication”, WHO has informed all member States to take “immediate steps” to ensure that all injectables are replaced with a fully-oral regimen that includes bedaquiline to treat…
WHO revises advice on use of delamanid drug in MDR-TB patients
In a Phase III trial, delamanid drug was found to be safe but the cure rate and mortality rate were not different between the group that received the delamanid drug…
A glimmer of hope as India’s war on TB gets more funding
There is a glimmer of hope with India registering a slight drop in the number of new tuberculosis cases and TB deaths in 2016 compared with 2015. From an estimated…
A looming threat of tuberculosis in children
The RNTCP guidelines on contact screening are heeded mostly in the breach. About 5,500 of over 76,000 children tested in nine Indian cities have been diagnosed with tuberculosis, 9% of…
