Editorial: A step closer to HIV prevention

Published in The Hindu on January 11, 2012   Time and again, HIV vaccine trials have proved right the dictum, ‘monkeys lie and mice do not always tell the truth'. Positive results in animals did not translate into good outcome in humans. However, the results of a recent study in rhesus monkeys show greater promise … Continue reading Editorial: A step closer to HIV prevention

Editorial: AIDS vaccine – a ray of hope

Published in The Hindu on September 24, 2011 The search for an effective AIDS vaccine began a quarter-century ago and after a series of failures, there finally appears some reason to cheer. The first signs of success are beginning to emerge, ironically, from a trial (RV144) that seemed destined to flop. The two vaccine candidates … Continue reading Editorial: AIDS vaccine – a ray of hope

Phase-I prime-boost AIDS vaccine trial shows modest immune response

Published in The Hindu on September 12, 2011 The final results of the Phase I prime-boost AIDS (Acquired Immune Deficiency Syndrome) vaccine trial started in February 2009 and conducted at the two sites — Tuberculosis Research Centre (TRC), Chennai, and the National AIDS Research Institute (NARI), Pune — has shown that the vaccines are safe … Continue reading Phase-I prime-boost AIDS vaccine trial shows modest immune response

Dedicated lab for HIV vaccine design

Published in The Hindu on March 3, 2011 After conducting a couple of AIDS vaccine trials in India, the New York based International AIDS Vaccine Initiative (IAVI) is shifting its focus to research that will help in finding more efficacious vaccines. The Department of Biotechnology (DBT) along with IAVI will soon establish and operate a … Continue reading Dedicated lab for HIV vaccine design

AIDS vaccine trial: prime-boost elicits modest immune response

Published in The Hindu on September 30, 2010 The preliminary results of the Phase I prime-boost AIDS vaccine trial started in February 2009 and conducted at the Tuberculosis Research Centre (TRC), Chennai and the National AIDS Research Institute (NARI), Pune, has shown that the vaccine used is safe and its ability to elicit immune response … Continue reading AIDS vaccine trial: prime-boost elicits modest immune response

Editorial: Hyping science

Published in The Hindu on November 6, 2009 When a two-decade-long search for an effective vaccine to prevent HIV infection has been a failure, the pressure to hype and provide spin to make results of a trial look successful increases. More so as only two trials have managed to reach Phase III, the final step … Continue reading Editorial: Hyping science

ALVAC-AIDSVAX AIDS vaccine unlikely to be a public health control measure

Published in The Hindu on October 22, 2009 The results of the Phase III AIDS vaccine trial using a prime-boost (ALVAC and AIDSVAX) vaccine undertaken in Thailand, published in The New England Journal of Medicine (NEJM), show that the vaccine is able to produce 31.2 per cent protection in those who are not infected at … Continue reading ALVAC-AIDSVAX AIDS vaccine unlikely to be a public health control measure

Phase I prime-boost AIDS vaccine trial on

Published in The Hindu on April 19, 2009 The first volunteer for the Phase I prime-boost AIDS vaccine trial, which will have a duration of two years, has been enrolled by the Tuberculosis Research Centre (TRC) here. “The first volunteer was enrolled on April 1, 2009” said V.D. Ramanathan, Senior Deputy Director, TRC, who is … Continue reading Phase I prime-boost AIDS vaccine trial on

Editorial: A glimmer of hope

Published in The Hindu on August 23, 2008 The search for a safe and efficacious AIDS vaccine has received a shot in the arm. The Phase I trial, aimed primarily at ascertaining the safety and HIV–specific immune response of a candidate vaccine, has yielded encouraging results in the exercise conducted at the Tuberculosis Research Centre, … Continue reading Editorial: A glimmer of hope

Phase I prime-boost vaccine trial to be conducted in Chennai, Pune

Published in The Hindu on August 16, 2008 Next year may see the start of a Phase I prime-boost AIDS vaccine trial at the National AIDS Research Institute (NARI), Pune, and the Tuberculosis Research Centre (TRC), Chennai. The prime to be used will be ADVAX, a DNA-based vaccine, and the boost will be the MVA … Continue reading Phase I prime-boost vaccine trial to be conducted in Chennai, Pune