Washing does not remove Salmonella bacteria from tomatoes, IISc team finds

IISc researchers have found that tomatoes get infected with Salmonella typhimurium, which cause gastroenteritis, when the bacteria enter the plant through tiny openings that form on the main root for the lateral roots to emerge. Hence, the bacteria are found inside tomatoes and cannot be removed by washing. As salinity increases the number of lateral roots … Continue reading Washing does not remove Salmonella bacteria from tomatoes, IISc team finds

MIT physicist raises a red flag on IISc superconductivity claim

Less than three weeks after Prof. Anshu Pandey and Dev Kumar Thapa from the Solid State and Structural Chemistry Unit at Indian Institute of Science (IISc) claimed to have achieved superconductivity at ambient temperature (below 236 K (-37 degree C)) and pressure, Dr. Brian Skinner, a physicist at the Massachusetts Institute of Technology, Boston has … Continue reading MIT physicist raises a red flag on IISc superconductivity claim

IISc researchers observe superconductivity at ambient temperature, pressure

IISc researchers have for the first time been able to achieve superconductivity at ambient temperature and pressure. The resistance observed is very low (10-4 ohms) but not zero. Though they didn’t observe perfect Meissner effect (where the magnetic fields are completely expelled by the superconducting state), they did observe samples becoming strongly diamagnetic, which is consistent with … Continue reading IISc researchers observe superconductivity at ambient temperature, pressure

Podcast: How cholesterol helps bacterial toxins kill cells

IISc researchers have found cholesterol present in cell membrane playing a central role in the two-step process of stabilising and binding together the pore-forming toxin Cytolysin A. On binding to cholesterol, the structure of the toxin protein that is bound to the cell membrane undergoes a change and is also stabilised. Cholesterol is also essential in … Continue reading Podcast: How cholesterol helps bacterial toxins kill cells

IISc researchers find cholesterol helps bacterial toxins kill cells

IISc researchers found cholesterol present in cell membrane plays a central role in the two-step process of stabilising and binding the pore-forming toxin Cytolysin A. On binding to cholesterol, the structure of the toxin protein that is bound to the cell membrane undergoes a change and is also stabilised. Cholesterol is also essential in holding together … Continue reading IISc researchers find cholesterol helps bacterial toxins kill cells

Podcast: FDA-approved asthma drug effectively treats TB

Archita Mishra and other researchers from IISc found that a FDA-approved asthma drug can be used for treating TB. Laboratory studies found the drug to be more effective in curtailing the growth of TB bacteria when used alone and in combination with anti-TB drugs — rifampicin and isoniazid. The drug was also able to prevent the … Continue reading Podcast: FDA-approved asthma drug effectively treats TB

IISc researchers find asthma drug effective in treating TB

Researchers at IISc used a FDA-approved asthma drug to treat TB. Laboratory studies found the drug to be more effective in curtailing the growth of TB bacteria when used alone and in combination with anti-TB drugs — rifampicin and isoniazid. The drug was also able to prevent the bacteria from causing inflammation thereby proving to be … Continue reading IISc researchers find asthma drug effective in treating TB

National portal to share research equipment, facility to be launched soon

CeNSE at IISc, Bengaluru will soon launch a national portal that has details of all government-funded research equipment and facilities available at academic institutions and organisations in India. Researchers from even colleges can now book, pay and use any equipment available in any research lab or organisation. The initiative will at least minimise duplication of … Continue reading National portal to share research equipment, facility to be launched soon

IISc team identifies a biomarker for early-stage Alzheimer’s

IISc researchers have ascertained that decrease in F-actin protein level results in early behavioural changes that would eventually lead to Alzheimer’s disease. F-actin thus behaves as an early biomarker of Alzheimer’s. Restoring the F-actin to normal levels resulted in Alzheimer mice behaving like healthy mice. IISc researchers have ascertained that decrease in F-actin protein level results in … Continue reading IISc team identifies a biomarker for early-stage Alzheimer’s

IISc researchers overthrow cancer metastasis dogma

IISc researchers have uncovered a novel mechanism by which cancer cells in circulation stay alive. They found the protein kinase AMPK gets activated when cancer cells detach from extracellular matrix, and, in turn, inhibits another protein kinase Akt. This finding overturns the two-decade dogma that Akt is vital for the survival of circulating cancer cells. The … Continue reading IISc researchers overthrow cancer metastasis dogma