A small inhibitor identified by researchers from the University of Hyderabad can block an enzyme (Rad51) that plays a crucial role in repairing DNA damage in malaria-causing Plasmodium falciparum. The inhibitor, when used along with anti-malaria drugs such as artemisinin, drastically increases the drug's effectiveness in both drug-sensitive and drug-resistant malaria. A small inhibitor that blocks … Continue reading University of Hyderabad’s inhibitor increases effectiveness of malaria drugs
Artemisinin resistance
A novel compound prevents, cures malaria
In a pathbreaking discovery, scientists from New Delhi’s International Centre for Genetic Engineering and Biotechnology (ICGEB), Broad Institute of MIT and Harvard and other institutions have isolated a compound that is able to completely clear malaria parasites with just a single, low-dose treatment. The compound acts on all three life stages of the malaria parasite, has prophylactic property … Continue reading A novel compound prevents, cures malaria
Artemisinin resistance dents the anti-malaria armour
The emergence of resistance to the artemisinin drug, a potent anti-malarial medicine, now threatens to affect the big gains achieved in recent years in reducing the global burden of malaria — an estimated 1.2 billion fewer malaria cases and 6.2 million fewer malaria deaths globally between 2001 and 2015. This resistance, to artemisinin, becomes all … Continue reading Artemisinin resistance dents the anti-malaria armour
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