New antimalarial agent shows promise

A new antimalarial compound (DDD107498) tested on mice and several mosquito species has shown great promise, says a study published today (June 18) in the journal Nature . The agent has all the attributes one would look for in an antimalarial drug — activity extending to multiple lifecycle stages of the malaria parasite. In several … Continue reading New antimalarial agent shows promise

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A trial drug raises hope to eradicate malaria

Published in The Hindu on March 21, 2013 A candidate drug (ELQ-300) was found capable of treating and preventing malaria infection, and even blocking transmission during a trial on mice. While the currently available drugs target the parasite at the blood stage of infection, the candidate drug was able to target both the liver and … Continue reading A trial drug raises hope to eradicate malaria

Artemisinin-resistant malaria has emerged in western Thailand

Published in The Hind on April 6, 2012 A team of researchers has sequenced the genome of Plasmodium falciparum and found that 33 regions on the genome appear to be under strong selection for artemisinin resistance. On further scrutiny, the team was able to narrow down to seven specific genes on chromosome 13. This particular … Continue reading Artemisinin-resistant malaria has emerged in western Thailand

Editorial: Unravelling the genetic make-up

Published in the Hindu on June 4, 2007 The battle to eradicate Aedes aegypti, the mosquito that causes yellow fever, dengue and chikungunya, has got a shot in the arm with the successful sequencing of the mosquito’s genome.  A. aegypti mosquito figures in about 50 million cases of dengue fever in tropical countries and about … Continue reading Editorial: Unravelling the genetic make-up

New antimalarial agent shows promise

Published in The Hindu on June 17, 2015 A new antimalarial compound (DDD107498) tested on mice and several mosquito species has shown great promise, says a study published today (June 18) in the journal Nature. The agent has all the attributes one would look for in an antimalarial drug — activity extending to multiple lifecycle … Continue reading New antimalarial agent shows promise