A small inhibitor identified by researchers from the University of Hyderabad can block an enzyme (Rad51) that plays a crucial role in repairing DNA damage in malaria-causing Plasmodium falciparum. The inhibitor, when used along with anti-malaria drugs such as artemisinin, drastically increases the drug's effectiveness in both drug-sensitive and drug-resistant malaria. A small inhibitor that blocks … Continue reading University of Hyderabad’s inhibitor increases effectiveness of malaria drugs
Plasmodium falciparum
Delhi researchers’ novel molecule prevents malaria disease
A team led by researchers from JNU and ICGEB, New Delhi has identified a molecule that prevents malaria parasites from invading red blood cells (RBCs) and causing the disease. It prevents the interaction between parasites and receptors found on RBCs thereby preventing the parasites from invading the RBCs. Since the molecule targets the receptors found on RBCs, it … Continue reading Delhi researchers’ novel molecule prevents malaria disease
A novel compound prevents, cures malaria
In a pathbreaking discovery, scientists from New Delhi’s International Centre for Genetic Engineering and Biotechnology (ICGEB), Broad Institute of MIT and Harvard and other institutions have isolated a compound that is able to completely clear malaria parasites with just a single, low-dose treatment. The compound acts on all three life stages of the malaria parasite, has prophylactic property … Continue reading A novel compound prevents, cures malaria
Editorial: Sri Lanka conquers malaria and how
In a huge public health achievement by a small island nation ravaged by prolonged civil war, Sri Lanka became a malaria-free country on September 5 when the World Health Organisation officially recognised it. The WHO certifies a country so when the chain of local transmission is interrupted for at least three consecutive years; the last reported case … Continue reading Editorial: Sri Lanka conquers malaria and how
The changing landscape of malaria parasite P. vivax’s resistance to drugs
The malaria parasite Plasmodium vivax found in South America and Asia evolves quickly in response to widely-used anti-malarial drugs, a genomic study published on June 27, 2016 in the journal Nature Genetics shows. The results are based on 200 samples collected from Southeast Asia (Thailand, Cambodia, Vietnam, Laos, Myanmar, and Malaysia) Oceania (Papua Indonesia and … Continue reading The changing landscape of malaria parasite P. vivax’s resistance to drugs