Rheumatoid arthritis: CDRI’s peptide effective in preventing cartilage destruction

CDRI researchers have used a specific fragment of a protein secreted by the parasitic worm liver fluke to protect the cartilage of joints from being destroyed, thus preventing rheumatoid arthritis from progressing. The peptide does not cause a wholesale suppression of the immune system. A specific fragment of a protein secreted by the parasitic worm … Continue reading Rheumatoid arthritis: CDRI’s peptide effective in preventing cartilage destruction

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Stimulating two receptors on macrophages helps clear TB bacteria

Researchers from IIT Ropar and CSIR-IMTECH have found that stimulating two specific receptors found on the macrophages helps in killing TB bacteria. Once activated, the macrophages eliminate the bacteria through autophagy. Activating the receptors leads to ten-fold reduction in anti-TB drug required to kill TB bacteria. Instead of using drugs to directly kill TB bacteria, … Continue reading Stimulating two receptors on macrophages helps clear TB bacteria

Machine learning-based model can determine if skin cancer can spread

Using machine learning of 17 genomic signatures, researchers from IIIT Delhi and CSIR-IMTECH have developed a webserver called CancerSPP that will help clinicians in classifying cutaneous melanoma as either primary or metastatic. The accuracy is over 89%, and both sensitivity and specificity are high. Using the expression of 17 key genes (messenger RNAs) it is … Continue reading Machine learning-based model can determine if skin cancer can spread

NPL synthesises novel security ink

NPL researchers have synthesised a security ink that emits intense red colour due to fluorescence when exposed to 254 nm wavelength UV and emits green colour due to phosphorescence soon after the UV source is turned off. A novel security ink that emits intense red colour when exposed to 254 nm wavelength UV and emits … Continue reading NPL synthesises novel security ink

IGIB finds a protein with better gene editing precision

IGIB researchers have used a different Cas9 protein derived from another bacteria to make gene editing more efficient and precise. The new Cas9 protein shows very less tendency to bind to off-target (unintended) sites on DNA. The new Cas9 protein was able to correct sickle cell anaemia mutation in patient-derived stem cells. Researchers at the Delhi-based … Continue reading IGIB finds a protein with better gene editing precision

CLRI’s biocatalyst cuts effluent discharge during leather processing

A novel biocatalyst developed by researchers at CLRI, Chennai speeds up the leather processing time at the pre-tanning stage, cuts chromium usage, and achieves three-fold reduction in water usage thus reducing waste discharge. A novel amylase-based biocatalyst developed by researchers at the Central Leather Research Institute (CSIR-CLRI), Chennai helps in the processing leather in an … Continue reading CLRI’s biocatalyst cuts effluent discharge during leather processing

CSIR-CDRI scientists take steps to correct mistakes in images

On June 6, two days after the report on image duplication in papers by CSIR-CDRI scientists was published, the director has instructed them to either send the correct image to the journal and get an erratum published or retract the paper if the mistake has an impact on the conclusion or if the mistake has … Continue reading CSIR-CDRI scientists take steps to correct mistakes in images

Chitra Mandal of CSIR-Indian Institute of Chemical Biology has seven more papers with manipulated images

Dr. Chitra Mandal, a SERB Distinguished Fellow at the CSIR-Indian Institute of Chemical Biology, Kolkata has seven more papers with problematic images — manipulation and/or duplication. These papers have been listed on Pubpeer. With this, there are 35 problematic papers by Dr. Mandal. The number of papers by Dr. Chitra Mandal, a SERB Distinguished Fellow at the CSIR-Indian … Continue reading Chitra Mandal of CSIR-Indian Institute of Chemical Biology has seven more papers with manipulated images

Chitra Mandal of CSIR-Indian Institute of Chemical Biology admits to ‘unintentional mistakes’; Nine more papers listed on Pubpeer

Dr. Chitra Mandal of CSIR-IICB has admitted to “unintentional mistakes” in her papers. Dr. Elisabeth M. Bik and another person have identified additional nine papers with image manipulation and/or duplication. With this the total number of papers with problematic images stands at 28. The last word has not been said yet. There important things happened … Continue reading Chitra Mandal of CSIR-Indian Institute of Chemical Biology admits to ‘unintentional mistakes’; Nine more papers listed on Pubpeer

19 papers of Chitra Mandal from CSIR-Indian Institute of Chemical Biology have duplicated images

Dr. Chitra Mandal, a SERB Distinguished Fellow at the CSIR-Indian Institute of Chemical Biology, Kolkata, has 19 papers listed on Pubpeer for image manipulation and/or duplication. She is the corresponding author in 17 papers. All the problematic images were double-checked by an independent expert. All the papers of Dr. Mandal that have been listed on … Continue reading 19 papers of Chitra Mandal from CSIR-Indian Institute of Chemical Biology have duplicated images