Phase-I prime-boost AIDS vaccine trial shows modest immune response

Published in The Hindu on September 12, 2011 The final results of the Phase I prime-boost AIDS (Acquired Immune Deficiency Syndrome) vaccine trial started in February 2009 and conducted at the two sites — Tuberculosis Research Centre (TRC), Chennai, and the National AIDS Research Institute (NARI), Pune — has shown that the vaccines are safe … Continue reading Phase-I prime-boost AIDS vaccine trial shows modest immune response

Dedicated lab for HIV vaccine design

Published in The Hindu on March 3, 2011 After conducting a couple of AIDS vaccine trials in India, the New York based International AIDS Vaccine Initiative (IAVI) is shifting its focus to research that will help in finding more efficacious vaccines. The Department of Biotechnology (DBT) along with IAVI will soon establish and operate a … Continue reading Dedicated lab for HIV vaccine design

AIDS vaccine trial: prime-boost elicits modest immune response

Published in The Hindu on September 30, 2010 The preliminary results of the Phase I prime-boost AIDS vaccine trial started in February 2009 and conducted at the Tuberculosis Research Centre (TRC), Chennai and the National AIDS Research Institute (NARI), Pune, has shown that the vaccine used is safe and its ability to elicit immune response … Continue reading AIDS vaccine trial: prime-boost elicits modest immune response

Editorial: AIDS vaccine prospects brighten

Published in The Hindu on May 2, 2009 The recent enrolment of the first volunteer at the Tuberculosis Research Centre in Chennai for a Phase I prime-boost AIDS vaccine clinical trial to be conducted simultaneously at the centre and the National AIDS Research Institute in Pune marks a new beginning in the search for a … Continue reading Editorial: AIDS vaccine prospects brighten

Phase I prime-boost AIDS vaccine trial on

Published in The Hindu on April 19, 2009 The first volunteer for the Phase I prime-boost AIDS vaccine trial, which will have a duration of two years, has been enrolled by the Tuberculosis Research Centre (TRC) here. “The first volunteer was enrolled on April 1, 2009” said V.D. Ramanathan, Senior Deputy Director, TRC, who is … Continue reading Phase I prime-boost AIDS vaccine trial on

Editorial: A glimmer of hope

Published in The Hindu on August 23, 2008 The search for a safe and efficacious AIDS vaccine has received a shot in the arm. The Phase I trial, aimed primarily at ascertaining the safety and HIV–specific immune response of a candidate vaccine, has yielded encouraging results in the exercise conducted at the Tuberculosis Research Centre, … Continue reading Editorial: A glimmer of hope

Phase I prime-boost vaccine trial to be conducted in Chennai, Pune

Published in The Hindu on August 16, 2008 Next year may see the start of a Phase I prime-boost AIDS vaccine trial at the National AIDS Research Institute (NARI), Pune, and the Tuberculosis Research Centre (TRC), Chennai. The prime to be used will be ADVAX, a DNA-based vaccine, and the boost will be the MVA … Continue reading Phase I prime-boost vaccine trial to be conducted in Chennai, Pune

India: AIDS vaccine trial results encouraging

Published in The Hindu on August 16, 2008 The final results of Phase I Modified Vaccinia Ankara (MVA)-based AIDS vaccine trial conducted at the Tuberculosis Research Centre (TRC) here and made available exclusively to this Correspondent, show that the vaccine is safe. Its ability to elicit HIV-specific immune responses in the volunteers was modest. “The … Continue reading India: AIDS vaccine trial results encouraging

Phase I prime-boost HIV vaccine trial planned

Published in The Hindu on August 11, 2008 The International AIDS Vaccine Initiative (IAVI), a New York based organisation, along with the ICMR and NACO, is planning to conduct Phase I HIV prime-boost vaccine trials in Chennai and Pune. In a mail to this Correspondent in May this year, Dr. Seth Berkley, President and CEO … Continue reading Phase I prime-boost HIV vaccine trial planned

Editorial: Lessons from AIDS vaccine trial

Published in The Hindu on February 8, 2008 The decision not to continue the clinical trial of the country’s first AIDS vaccine based on the results of the Phase I trial is a setback for further research. The trial at the National AIDS Research Institute, Pune (NARI) using the adeno-associated virus (AAV) vector, started in … Continue reading Editorial: Lessons from AIDS vaccine trial