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Category: AstraZeneca

Posted on January 3, 2021

Why people with prior SARS-CoV-2 infection still need to be vaccinated

Since vaccine shortage is expected to last at least for a few months, it may seem appealing to delay or avoid vaccinating those who have been naturally infected. But does…

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Posted on January 2, 2021

UK uses an untested strategy to rapidly but partially protect people at risk

With the virus running amok in the country and vaccines in short-supply, the U.K. is attempting an untested strategy of delaying the second dose of both AstraZeneca and Pfizer vaccine even in the absence of data from large trials. The intent is to rapidly but partially protect more individuals who are at risk.

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Posted on December 19, 2020

COVID-19: Ethical challenges of vaccinating people with comorbidities

Unlike in other groups, national databases of people with comorbidities are not available. However, though not comprehensive, since 2010, State governments have been conducting population-based district level screening to detect…

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Posted on December 12, 2020

Can COVID-19 vaccines with EUA be used at the population level?

Meanwhile, the Indian government has spelt out four high-risk groups — healthcare workers, frontline workers, those over 50 years of age and those aged below 50 years but with co-morbidities…

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Posted on December 11, 2020

By putting the vaccine approval on hold for want of data, DCGI has underscored its priorities

The greatly reassuring decision to seek additional safety and immunogenicity data from the Pune-based Serum Institute of India and Hyderabad’s Bharat Biotech underlines the regulator’s priorities even for emergency use…

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Posted on December 8, 2020December 8, 2020

Transparency in COVID-19 vaccine trials vital to gain public trust

Unlike Pfizer, AstraZeneca, which is carrying out the phase-3 trials of the Oxford vaccine in four countries, is yet to secure a nod from any of the regulatory agencies despite…

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Posted on November 23, 2020November 23, 2020

Oxford vaccine shows 90% efficacy in Phase-3 trial

Two doses of the vaccine given in two different regimen showed different efficacies. In the case of the regimen (involving 2,741 participants) where a halved dose was used as a…

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Posted on November 12, 2020November 12, 2020

Pfizer’s COVID-19 vaccine shows promise, many unknowns remain

The results of the Phase-1 trial, announced in August, first through a press release and then through a preprint a week later, showed that the vaccine induced neutralising antibodies and…

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