NCCS researchers have found a way to expand hematopoietic stem cells before transplantation and also improve the engraftment potential. Mesenchymal stem cells treated with a nitric oxide donor secreted micro-vesicles containing certain factors that increase the engraftment potential of hematopoietic stem cells. One of the reasons why the efficiency of bone marrow transplantation gets compromised is due to … Continue reading NCCS’ new approach makes bone marrow transplantation more successful
Bone marrow
NCCS’ novel approach improves success rate of bone marrow transplantation
Researchers from Pune’s National Centre for Cell Science (NCCS) have found that co-culturing aged haematopoietic stem cells with young mesenchymal stromal cells will rejuvenate the stem cells and improve their functionality. When done prior to transplantation, the rejuvenation will help improve the engrafting efficiency of stem cells. This novel method will expand the pool of donors for bone … Continue reading NCCS’ novel approach improves success rate of bone marrow transplantation
Amputation: Smokers learnt the hard way
G. Ranganathan, a 50-year-old man from Thanjavur district, Tamil Nadu, is one of the 44 patients whose leg has been saved by stem cell treatment. He had already lost his right leg due to TAO. He has been smoking for the last 25-odd years. “My right leg was amputated in 2005 and doctors had advised … Continue reading Amputation: Smokers learnt the hard way
Bone marrow stem cell treatment saves legs
Published in The Hindu on August 6, 2009 The results of a clinical trial to save volunteers’ leg from amputation by injecting stem cell concentrate to the limb affected by thrombo angitis obliterance (TAO) have been encouraging. The stem cells were taken from the patients’ bone marrow. The clinical trial is being conducted on patients … Continue reading Bone marrow stem cell treatment saves legs