Combination therapy using malaria drug quickly clears TB
IISc researchers have discovered the mechanism by which TB bacteria develop tolerance to TB drugs. They found a combination of malaria and TB drug can prevent the bacteria from developing…
Category: Tuberculosis (TB)
Stimulating two receptors on macrophages helps clear TB bacteria
Researchers from IIT Ropar and CSIR-IMTECH have found that stimulating two specific receptors found on the macrophages helps in killing TB bacteria. Once activated, the macrophages eliminate the bacteria through…
Novel way found to kill dormant TB bacteria in stem cells
Delhi-based researchers have found that TB bacteria promote rapid synthesis of lipids inside mesenchymal stem cells and hide within the lipid droplets so created. They found that TB bacteria hijack the…
Cheap, filter-based kits developed for TB diagnosis, drug-resistance testing
Three cheap, filter-based kits developed by a multi-institutional team and an industry partner improves the sensitivity of LED fluorescence microscopy by 5%, enable transport of sputum samples at ambient conditions…
Pretomanid: XDR-TB may soon become easily treatable
Though the total number of people with XDR-TB and treatment intolerant or non-responsive MDR-TB who will require the new anti-TB drug Pretomanid may not be high, these are people who…
Explainer: What makes the new drug-resistant TB medicine Pretomanid promising
When used in combination with bedaquiline and linezolid, the newly approved pretomanid drug for MDR-TB and XDR-TB had an overall treatment success rate of about 90%. Besides better effectiveness, the…
Tweaked pharmacy referral model increases TB case-finding in Patna
Tweaking the existing pharmacy referral system in Patna brought huge benefits. Instead of referring symptomatic TB patients to doctor for consultation, referring them for an X-ray before consulting a doctor…
IGIB unravels a new mechanism TB bacteria use to subvert host defence
IGIB researchers have found that besides degradative pathways, TB bacteria actively manipulate another organelle — lipid droplets in macrophages. When lipid droplets are infected with TB bacteria, the composition of…
