A Science and Technology Blog
IGIB researchers have found that besides degradative pathways, TB bacteria actively manipulate another organelle — lipid droplets in macrophages. When lipid droplets are infected with TB bacteria, the composition of…
Delhi researchers have identified a protein that is vital for the formation of biofilm by TB-causing bacteria and other bacterial species. Two FDA-approved drugs (acarbose and cyclosporine-A) bind to the…
Tarun Sharma explains how the team developed highly sensitive and specific diagnostic tests for pulmonary TB and pleural TB. The diagnostic tests make use of a DNA aptamer that shows high…
Researchers have developed highly sensitive and specific diagnostic tests for pulmonary TB and pleural TB. The diagnostic tests make use of a DNA aptamer that shows high binding affinity to a…
In a Phase IIb trail, bedaquiline drug for MDR-TB treatment was found to be cardiotoxic and hepatotoxic, and it also caused more deaths. Review of evidence in 2015 showed a…
Amit Singh from IISc explains how a protein (WhiB4) that condenses the DNA of TB-causing bacteria in response to oxidative stress was identified. The team found that artificially elevating the…
IISc researchers have for the first time identified a protein (WhiB4) that condenses the DNA of TB-causing bacteria in response to oxidative stress. They found that artificially elevating the levels of WhiB4…
A team lead by Jaya Sivaswami Tyagi from AIIMS in collaboration with THSTI has developed a diagnostic test for TB meningitis with nearly 100% sensitivity and about 91% specificity. The rapid, point-of-care…
