IISER Pune researchers produce a novel drug-delivery system to kill cancer cells

Researchers at the Indian Institute of Science Education and Research (IISER) Pune have successfully developed a novel cancer drug-delivery system using graphene oxide nanoparticles. In a serendipitous discovery, a team led by Dr. Sudipta Basu and Dr. Nirmalya Ballav from the Department of Chemistry found that when a FDA-approved anticancer drug cisplatin was added, the... Continue Reading →

Flat lying posture doesn’t do much for stroke treatment

There is no significant difference in the disability outcomes for patients who have suffered acute stroke, whether they received treatment lying flat on the back with the face upwards or in a sitting-up position with the head elevated to at least 30 degrees. This is the conclusion of a major trial that involved over 11,000... Continue Reading →

IISc’s blood cancer drug shows early promise

Researchers at the Indian Institute of Science, Bengaluru have synthesised a small molecule that shows a degree of promise as an anticancer agent. In particular, the inhibitor was effective against leukaemia. The work was done in collaboration with researchers from the University of Mysore. The molecule (benzothiazole derivative), codenamed 5g, was found to be effective... Continue Reading →

CCMB develops a novel drug-delivery system for treating keratitis eye infection

Scientists at the Hyderabad-based CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB) have developed a novel drug-delivery system for treating fungal keratitis. Keratitis is the inflammation of the eye, which starts with redness and itching and might eventually lead to blindness. Keratitis is caused by both bacteria and fungi. Fungi attach themselves to the cornea and... Continue Reading →

Nearly 50% of diabetics identified in 14 Indian States unaware of their condition

A large community-based study involving over 57,000 adults from 14 States and a Union Territory (Chandigarh) in the country has revealed that the average prevalence of diabetes in these States stands at 7.3%. The prevalence varied from 4.3% of the population in the case of Bihar, to 10.4% in Tamil Nadu; Chandigarh was found to... Continue Reading →

Bharat Biotech has begun chikungunya vaccine Phase I trial

The Hyderabad-based Bharat Biotech has begun a Phase I human clinical trial of the indigenously developed chikungunya vaccine three months ago. The vaccine uses a killed virus. The Phase I trial will test mainly for safety and the ability of the vaccine to provoke an immune response in the body. The higher the immune response... Continue Reading →

Wolbachia-infected mosquitoes less capable of spreading Zika, chikunguya

With conventional vector controlling measures against dengue- and Zika-causing Aedes aegypti mosquitoes failing, several countries have started caged and even open field trials using genetically modified mosquitoes. India has signed a Memorandum of Understanding with Monash University for using Wolbachia-infected A. aegypti mosquitoes for vector control. Dengue, Zika or chikunguya viruses cannot replicate when mosquitoes have been infected... Continue Reading →

Seventy-year journey of Zika virus

Zika is an arbovirus infection which occurs through the bite of several different species of Aedes mosquitoes, including the Aedes aegypti which is active during the day; it can also be transmitted sexually. The virus was first isolated from a rhesus monkey in Uganda in the Zika forest, near the western shore of Lake Victoria,... Continue Reading →

Improving access to mental health services in remote areas

While about 10% of the population in India suffers from common mental disorders, only about 15-25% of this receives mental health care. But a small-scale study carried out on approximately 5,000 people living in 30 tribal villages in West Godavari district of Andhra Pradesh was able to improve the practice of seeking out mental health... Continue Reading →

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