Researchers at the Institute of Life Sciences, Bhubaneswar have identified the novel mechanism by which misfolded proteins form aggregates and get degraded in the cells. They have discovered that downregulation of TRIM16 protein may help in treating cancers, while activation of the TRIM16 protein may have therapeutic benefits in the case of neurodegerative diseases such as Alzheimer’s, Parkinson’s and amyotrophic lateral sclerosis.